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| Cat.No | ACP17987 | Target Name | NFX1 |
|---|---|---|---|
| Target Synonyms | NFX1; NFX2; Transcriptional repressor NF-X1; EC 2.3.2.-; Nuclear transcription factor; X box-binding protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q12986 |
|---|
Uniprot Id
Q12986
Target Species
Human
Target Name
NFX1
Target Full Name
Transcriptional repressor NF-X1
Target Function
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
Target Subcellular Location
Nucleus.
Target Protein Families
NFX1 family
Target Synonyms
NFX1; NFX2; Transcriptional repressor NF-X1; EC 2.3.2.-; Nuclear transcription factor; X box-binding protein 1
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