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| Cat.No | ACP14604 | Target Name | GUF1 |
|---|---|---|---|
| Target Synonyms | GUF1; Translation factor GUF1; mitochondrial; EC 3.6.5.-; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 50-669 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N442 |
|---|
Uniprot Id
Q8N442
Target Species
Human
Target Name
GUF1
Target Full Name
Translation factor GUF1, mitochondrial
Target Function
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Target Involvement
Epileptic encephalopathy, early infantile, 40 (EIEE40)
Target Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Target Protein Families
TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, LepA subfamily
Target Synonyms
GUF1; Translation factor GUF1; mitochondrial; EC 3.6.5.-; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase
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