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Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 (TMIGD2), Truncated

ACP13238

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13238 Target NameTMIGD2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96BF3
Background Information
  • Uniprot Id

    Q96BF3

  • Target Species

    Human

  • Target Name

    TMIGD2

  • Target Full Name

    Transmembrane and immunoglobulin domain-containing protein 2

  • Target Function

    Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands

  • Target Synonyms

    CD28H; IGPR 1; IGPR1; immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; TMIG2_HUMAN; TMIGD2; Transmembrane and immunoglobulin domain containing 2; Transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879

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