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| Cat.No | ACP06456 | Target Name | TMPRSS3 |
|---|---|---|---|
| Target Synonyms | TMPRSS3; ECHOS1; TADG12; UNQ323/PRO382; Transmembrane protease serine 3; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P57727 |
|---|
Uniprot Id
P57727
Target Species
Human
Target Name
TMPRSS3
Target Full Name
Transmembrane protease serine 3
Target Function
Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro).
Target Involvement
Deafness, autosomal recessive, 8 (DFNB8)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
Target Synonyms
TMPRSS3; ECHOS1; TADG12; UNQ323/PRO382; Transmembrane protease serine 3; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein
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