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| Cat.No | ACP08655 | Target Name | TMEM150B |
|---|---|---|---|
| Target Synonyms | TMEM150B; TMEM224; Modulator of macroautophagy TMEM150B; Protein DRAM-3; Transmembrane protein 150B; Transmembrane protein 224 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A6NC51 |
|---|
Uniprot Id
A6NC51
Target Species
Human
Target Name
TMEM150B
Target Full Name
Modulator of macroautophagy TMEM150B
Target Function
Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux. Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner. May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Target Protein Families
DRAM/TMEM150 family
Target Tissue Specificity
Highly expressed in the colon and lung with comparatively high levels also detectable in the lymph nodes, placenta, duodenum, peripheral blood mononuclear cells and spleen.
Target Synonyms
TMEM150B; TMEM224; Modulator of macroautophagy TMEM150B; Protein DRAM-3; Transmembrane protein 150B; Transmembrane protein 224
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