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| Cat.No | ACP08611 | Target Name | TMEM170B |
|---|---|---|---|
| Target Synonyms | TMEM170B; Transmembrane protein 170B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T4T1 |
|---|
Uniprot Id
Q5T4T1
Target Species
Human
Target Name
TMEM170B
Target Full Name
Transmembrane protein 170B
Target Function
Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
TMEM170 family
Target Tissue Specificity
Expressed in normal breast tissues. Down-regulated in breast cancer cells (at protein level).
Target Synonyms
TMEM170B; Transmembrane protein 170B
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