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| Cat.No | ACP06256 | Target Name | TMEM63C |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P1W3 |
|---|
Uniprot Id
Q9P1W3
Target Species
Human
Target Name
TMEM63C
Target Full Name
Calcium permeable stress-gated cation channel 1
Target Function
Acts as an osmosensitive calcium-permeable cation channel. Required for the functional integrity of the kidney glomerular filtration barrier.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
CSC1 (TC 1.A.17) family
Target Tissue Specificity
Expressed in podocytes of kidney glomeruli. Significantly reduced expression in patients with focal segmental glomerulosclerosis.
Target Synonyms
4932420N09; 9330187M14Rik; C14orf171; Calcium permeable stress gated cation channel 1 homolog; Calcium permeable stress-gated cation channel 1; Chromosome 14 open reading frame 171; CSC1; CSC1_HUMAN; DKFZp434P0111; hsCSC1; RGD1310207; TMEM63C; Transmembrane protein 63C
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