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Recombinant Human Tripartite motif-containing protein 72 (TRIM72), Truncated

ACP16427

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Specifications

Cat.No	ACP16427	Target Name	TRIM72
Target Synonyms	LOC493829; Mg53; Mitsugumin-53; TRI72_HUMAN; trim72; Tripartite motif containing 72; Tripartite motif containing protein 72 ; Tripartite motif-containing protein 72	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-269
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6ZMU5

Background Information

Uniprot Id

Q6ZMU5
Target Species

Human
Target Name

TRIM72
Target Full Name

Tripartite motif-containing protein 72
Target Function

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
Target Subcellular Location

Cell membrane, sarcolemma. Cytoplasmic vesicle membrane.
Target Protein Families

TRIM/RBCC family
Target Research Area

Transport, Cell Biology
Target Synonyms

LOC493829; Mg53; Mitsugumin-53; TRI72_HUMAN; trim72; Tripartite motif containing 72; Tripartite motif containing protein 72 ; Tripartite motif-containing protein 72

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Recombinant Human Tripartite motif-containing protein 72 (TRIM72), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Tripartite motif-containing protein 72 (TRIM72), Truncated Now

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