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| Cat.No | ACP21583 | Target Name | TULP1 |
|---|---|---|---|
| Target Synonyms | RP14; Tubby like protein 1; Tubby related protein 1 (Tubby like protein 1); Tubby related protein 1; Tubby-like protein 1; Tubby-related protein 1; TUBL1; TULP 1; Tulp1; TULP1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-542aa |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00294 |
|---|
Uniprot Id
O00294
Target Species
Human
Target Name
TULP1
Target Full Name
Tubby-related protein 1
Target Function
Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long-term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
Target Involvement
Retinitis pigmentosa 14 (RP14); Leber congenital amaurosis 15 (LCA15)
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Secreted. Cell junction, synapse.
Target Protein Families
TUB family
Target Tissue Specificity
Retina-specific.
Target Synonyms
RP14; Tubby like protein 1; Tubby related protein 1 (Tubby like protein 1); Tubby related protein 1; Tubby-like protein 1; Tubby-related protein 1; TUBL1; TULP 1; Tulp1; TULP1_HUMAN
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