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| Cat.No | ACP09637 | Target Name | YARS2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 17-477 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2Z4 |
|---|
Uniprot Id
Q9Y2Z4
Target Species
Human
Target Name
YARS2
Target Full Name
Tyrosine--tRNA ligase, mitochondrial
Target Function
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Target Involvement
Myopathy with lactic acidosis and sideroblastic anemia 2 (MLASA2)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
CGI 04; FLJ13995; mitochondrial; MLASA2; mt TyrRS; SYYM_HUMAN; Tyrosine tRNA ligase 2 mitochondrial; Tyrosine tRNA ligase; Tyrosine tRNA ligase mitochondrial; Tyrosine--tRNA ligase; Tyrosyl tRNA synthetase 2 mitochondrial; Tyrosyl tRNA synthetase mitochondrial precursor; Tyrosyl-tRNA synthetase; TyrRS; YARS 2; YARS2
Target Background
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
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