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| Cat.No | ACP12991 | Target Name | UBLCP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-318 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WVY7 |
|---|
Uniprot Id
Q8WVY7
Target Species
Human
Target Name
UBLCP1
Target Full Name
Ubiquitin-like domain-containing CTD phosphatase 1
Target Function
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
Target Subcellular Location
Nucleus. Note=Colocalizes with nuclear proteasomes.
Target Tissue Specificity
Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.
Target Synonyms
CPUB1; CTD like phosphatase domain containing protein; CTD phosphatase like with ubiquitin domain 1; FLJ25267; MGC10067; Nuclear proteasome inhibitor UBLCP1; UBCP1_HUMAN; Ubiquitin like domain containing CTD phosphatase 1; Ubiquitin-like domain-containing CTD phosphatase 1; UBLCP1
Target Background
Enables protein serine/threonine phosphatase activity. Involved in protein dephosphorylation. Located in nucleolus and nucleoplasm.
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