Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP01157 | Target Name | ZRANB1 |
|---|---|---|---|
| Target Synonyms | (TRAF-binding domain-containing protein)(hTrabid)(Zinc finger Ran-binding domain-containing protein 1) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-708aa |
| Mol Weight | 88.4 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UGI0 |
|---|
Uniprot Id
Q9UGI0
Target Species
Human
Target Name
ZRANB1
Target Full Name
Ubiquitin thioesterase ZRANB1
Target Function
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Target Protein Families
Peptidase C64 family
Target Tissue Specificity
Widely expressed.
Target Research Area
Others
Target Synonyms
DKFZp762P2216; hTrabid; Trabid; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; ZRAN1_HUMAN; ZRANB1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
