Home Products Proteins Recombinant Proteins Recombinant Human Uncharacterized protein C18orf1 (C18orf1), Truncated

Recombinant Human Uncharacterized protein C18orf1 (C18orf1), Truncated

ACP06415

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP06415	Target Name	LDLRAD4
Target Synonyms	LDLRAD4; C18orf1; Low-density lipoprotein receptor class A domain-containing protein 4	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O15165

Background Information

Uniprot Id

O15165
Target Species

Human
Target Name

LDLRAD4
Target Full Name

Low-density lipoprotein receptor class A domain-containing protein 4
Target Function

Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal
Target Subcellular Location

Early endosome membrane; Single-pass membrane protein.
Target Protein Families

PMEPA1 family
Target Tissue Specificity

Expressed in lymphocytes.
Target Synonyms

LDLRAD4; C18orf1; Low-density lipoprotein receptor class A domain-containing protein 4

Inquire Recombinant Human Uncharacterized protein C18orf1 (C18orf1), Truncated Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Uncharacterized protein C18orf1 (C18orf1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Uncharacterized protein C18orf1 (C18orf1), Truncated Now

Related Products