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| Cat.No | ACP15608 | Target Name | C2CD5 |
|---|---|---|---|
| Target Synonyms | C2CD5; CDP138; KIAA0528C2 domain-containing protein 5; C2 domain-containing phosphoprotein of 138 kDa | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86YS7 |
|---|
Uniprot Id
Q86YS7
Target Species
Human
Target Name
C2CD5
Target Full Name
C2 domain-containing protein 5
Target Function
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
Target Subcellular Location
Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
Target Synonyms
C2CD5; CDP138; KIAA0528C2 domain-containing protein 5; C2 domain-containing phosphoprotein of 138 kDa
Target Background
Enables calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in cellular response to insulin stimulus; intracellular protein transmembrane transport; and positive regulation of transport. Located in several cellular components, including centriolar satellite; cytoplasmic vesicle membrane; and ruffle membrane.
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