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| Cat.No | ACP10316 | Target Name | C12orf10 |
|---|---|---|---|
| Target Synonyms | C12orf10; UPF0160 protein MYG1; mitochondrial | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 48-376 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HB07 |
|---|
Uniprot Id
Q9HB07
Target Species
Human
Target Name
MYG1
Target Full Name
MYG1 exonuclease
Target Function
3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable).
Target Subcellular Location
Nucleus, nucleoplasm. Mitochondrion matrix. Nucleus, nucleolus.
Target Protein Families
UPF0160 (MYG1) family
Target Tissue Specificity
Ubiquitously expressed, with highest levels in testis.
Target Synonyms
C12orf10; UPF0160 protein MYG1; mitochondrial
Target Background
Predicted to enable nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to act upstream of or within locomotory exploration behavior. Located in mitochondrion and nucleoplasm.
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