Home Products Recombinant Human Uroplakin-3b (UPK3B), Truncated

Recombinant Human Uroplakin-3b (UPK3B), Truncated

ACP12202

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Specifications

Cat.No	ACP12202	Target Name	UPK3B
Target Synonyms	FLJ32198; MGC10902; p35; UP3b; UPIIIb; UPK3B; UPK3B_HUMAN; uroplakin 3B; Uroplakin IIIb; Uroplakin-3b	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BT76

Background Information

Uniprot Id

Q9BT76
Target Species

Human
Target Name

UPK3B
Target Full Name

Uroplakin-3b
Target Function

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

Uroplakin-3 family
Target Synonyms

FLJ32198; MGC10902; p35; UP3b; UPIIIb; UPK3B; UPK3B_HUMAN; uroplakin 3B; Uroplakin IIIb; Uroplakin-3b
Target Background

UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).

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Recombinant Human Uroplakin-3b (UPK3B), Truncated

Specifications

Immunogen Information

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