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| Cat.No | ACP20822 | Target Name | UTS2 |
|---|---|---|---|
| Target Synonyms | PRO1068; U-II; UCN2; UII; Urotensin 2 preproprotein isoform a; Urotensin 2 preproprotein isoform b; Urotensin II; Urotensin-2; UTS2; UTS2_HUMAN; UTSII | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 114-124 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95399 |
|---|
Uniprot Id
O95399
Target Species
Human
Target Name
UTS2
Target Full Name
Urotensin-2
Target Function
Highly potent vasoconstrictor.
Target Subcellular Location
Secreted.
Target Protein Families
Urotensin-2 family
Target Tissue Specificity
Brain specific.
Target Synonyms
PRO1068; U-II; UCN2; UII; Urotensin 2 preproprotein isoform a; Urotensin 2 preproprotein isoform b; Urotensin II; Urotensin-2; UTS2; UTS2_HUMAN; UTSII
Target Background
This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.
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