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| Cat.No | ACP15327 | Target Name | VPS37D |
|---|---|---|---|
| Target Synonyms | ESCRT-I complex subunit VPS37D; MGC35352; Vacuolar protein sorting-associated protein 37D; VP37D_HUMAN; VPS37D; WBSCR24; Williams-Beuren syndrome chromosomal region 24 protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-251 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86XT2 |
|---|
Uniprot Id
Q86XT2
Target Species
Human
Target Name
VPS37D
Target Full Name
Vacuolar protein sorting-associated protein 37D
Target Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Target Involvement
VPS37D is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
Target Subcellular Location
Late endosome membrane; Peripheral membrane protein.
Target Protein Families
VPS37 family
Target Synonyms
ESCRT-I complex subunit VPS37D; MGC35352; Vacuolar protein sorting-associated protein 37D; VP37D_HUMAN; VPS37D; WBSCR24; Williams-Beuren syndrome chromosomal region 24 protein
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