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| Cat.No | ACP18241 | Target Name | VEPH1 |
|---|---|---|---|
| Target Synonyms | 2810471M23Rik; MELT; MELT_HUMAN; Protein melted; RGD1308217; Ventricular zone-expressed PH domain-containing protein homolog 1; VEPH; Veph1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14D04 |
|---|
Uniprot Id
Q14D04
Target Species
Human
Target Name
VEPH1
Target Full Name
Ventricular zone-expressed PH domain-containing protein homolog 1
Target Function
Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
MELT/VEPH family
Target Synonyms
2810471M23Rik; MELT; MELT_HUMAN; Protein melted; RGD1308217; Ventricular zone-expressed PH domain-containing protein homolog 1; VEPH; Veph1
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