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| Cat.No | ACP17642 | Target Name | WASHC4 |
|---|---|---|---|
| Target Synonyms | Kiaa1033; WAHS4_HUMAN; WAHS7_HUMAN; WASH complex subunit 7; WASHC4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2M389 |
|---|
Uniprot Id
Q2M389
Target Species
Human
Target Name
WASHC4
Target Full Name
WASH complex subunit 4
Target Function
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
Target Involvement
Mental retardation, autosomal recessive 43 (MRT43)
Target Subcellular Location
Early endosome.
Target Protein Families
SWIP family
Target Synonyms
Kiaa1033; WAHS4_HUMAN; WAHS7_HUMAN; WASH complex subunit 7; WASHC4
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