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| Cat.No | ACP18370 | Target Name | ZMYM3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14202 |
|---|
Uniprot Id
Q14202
Target Species
Human
Target Name
ZMYM3
Target Full Name
Zinc finger MYM-type protein 3
Target Function
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Target Involvement
A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.
Target Synonyms
DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type protein 3; Zinc finger MYM-type protein 3; Zinc finger protein 261; ZMYM 3; Zmym3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; ZNF261
Target Background
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
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