Recombinant Human Zinc finger protein 143 (ZNF143)

ACP22866

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Specifications

Cat.No	ACP22866	Target Name	ZNF143
Target Synonyms	ZNF143; SBF; STAF; Zinc finger protein 143; SPH-binding factor; Selenocysteine tRNA gene transcription-activating factor; hStaf	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-638
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P52747

Background Information

Uniprot Id

P52747
Target Species

Human
Target Name

ZNF143
Target Full Name

Zinc finger protein 143
Target Function

Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
Target Subcellular Location

Nucleus.
Target Protein Families

GLI C2H2-type zinc-finger protein family
Target Tissue Specificity

Expressed in all tissues tested, with the strongest expression in ovary.
Target Synonyms

ZNF143; SBF; STAF; Zinc finger protein 143; SPH-binding factor; Selenocysteine tRNA gene transcription-activating factor; hStaf
Target Background

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of snRNA transcription by RNA polymerase II. Predicted to be located in nucleoplasm.

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Recombinant Human Zinc finger protein 143 (ZNF143)

Specifications

Immunogen Information

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