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| Cat.No | ACP19474 | Target Name | ZNF410 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-478 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VK4 |
|---|
Uniprot Id
Q86VK4
Target Species
Human
Target Name
ZNF410
Target Full Name
Zinc finger protein 410
Target Function
Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3' in regulatory elements and modulates transcription of target genes. Indirectly represses transcription of HBG1 and HBG2, hemoglobin subunits gamma-1 and gamma-2, in erythroid cells, via direct transcriptional activation of the chromodomain protein CHD4, a component of the NuRD complex. Activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. Activates transcription of the gap junction gene GJC1, perhaps in response to increasing glucose.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Widely expressed.
Target Synonyms
Another partner for ARF 1; APA 1; APA1; Clones 23667 and 23775 zinc finger protein; D12Ertd748e; Zfp410; Zinc finger protein 410; Zinc finger protein APA 1; Zinc finger protein APA-1; ZN410_HUMAN; Znf410
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