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The recombinant antibody against TNFRSF9/4-1BB was produced using the Recombinant Human TNFRSF9 protein as the immunogen. This antibody exists as a non-conjugated isotype hIgG2, Affinity-chromatography purified. This antibody has been validated on ELISA.
The recombinant antibody against TNFRSF9/4-1BB was produced using the Recombinant Human TNFRSF9 protein as the immunogen. This antibody exists as a non-conjugated isotype hIgG2, Affinity-chromatography purified. This antibody has been validated on ELISA.
$350.00
| Cat.No | ADC-56720A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | TNFRSF9/4-1BB | Target Synonyms | 4 1BB; 4 1BB ligand receptor; 4-1BB ligand receptor; 4-1BB Ligand Receptor T Cell; 4-1BB, mouse |
| Form | Liquid | Species Reactivity | Human |
| Isotype | hIgG2 | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human TNFRSF9 protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q07011 |
Uniprot Id
Q07011
Target Species
Human
Target Name
TNFRSF9
Target Full Name
Tumor necrosis factor receptor superfamily member 9
Target Function
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed on the surface of activated T-cells.
Target Synonyms
ILA; 4-1BB; CD137; CDw137; IMD109; 4-1BB/CD137
Target Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
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