Rabbit anti-Human SLC5A5 Polyclonal Antibody

The antibody against SLC5A5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11607A

Number

Cat.No	ADA-11607A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SLC5A5
Target Synonyms	NIS; TDH1; SLC5A5	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	SGC-7901, THP-1	Application	ELISA, WB

Cat.No

ADA-11607A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SLC5A5

Target Synonyms

NIS; TDH1; SLC5A5

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

SGC-7901, THP-1

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1).	Target Species	Human
Immunogen Sequence	ALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL	Uniprot ID	Q92911

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1).

Target Species

Human

Immunogen Sequence

ALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL

Uniprot ID

Q92911

Background Information

Uniprot Id

Q92911
Target Species

Human
Target Name

SLC5A5
Target Full Name

Sodium/iodide cotransporter
Target Function

Mediates iodide uptake in the thyroid gland.
Target Involvement

Thyroid dyshormonogenesis 1 (TDH1)
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Sodium:solute symporter (SSF) (TC 2.A.21) family
Target Tissue Specificity

Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
Target Research Area

Others
Target Synonyms

Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na+/I- cotransporter; Na+/I-symporter; NIS; SC5A5_HUMAN; Slc5a5; sodium iodide symporter; Sodium-iodide symporter; Sodium/iodide cotransporter; Solute carrier family 5 (sodium iodide symporter) member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; Solute carrier family 5 member 5; TDH1
Target Background

This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.

Rabbit anti-Human SLC5A5 Polyclonal Antibody

Specifications

Immunogen Information

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