Rabbit anti-Human SRP54 Monoclonal Antibody

The antibody against SRP54 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-504 of human SRP54 (P61011) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-13232A

Number

Cat.No	ADA-13232A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SRP54
Target Synonyms	SCN8; SRP54	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Jurkat	Application	ELISA, WB, IF/ICC

Cat.No

ADA-13232A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SRP54

Target Synonyms

SCN8; SRP54

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Jurkat

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 400-504 of human SRP54 (P61011).	Target Species	Human
Immunogen Sequence	PGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM	Uniprot ID	P61011

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 400-504 of human SRP54 (P61011).

Target Species

Human

Immunogen Sequence

PGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM

Uniprot ID

P61011

Background Information

Uniprot Id

P61011
Target Species

Human
Target Name

SRP54
Target Full Name

Signal recognition particle subunit SRP54
Target Function

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
Target Subcellular Location

Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Target Protein Families

GTP-binding SRP family, SRP54 subfamily
Target Research Area

Signal Transduction
Target Synonyms

Signal recognition particle 54 kDa protein; Signal recognition particle 54kDa; SRP 54; SRP54; SRP54_HUMAN
Target Background

Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiation and protein targeting to ER. Located in cytosol and nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. Implicated in severe congenital neutropenia 8.

Rabbit anti-Human SRP54 Monoclonal Antibody

Specifications

Immunogen Information

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