Rabbit anti-Human RASSF2 Monoclonal Antibody

The antibody against RASSF2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2 (P50749) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13387A

Number

Cat.No	ADA-13387A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	RASSF2
Target Synonyms	CENP-34; RASFADIN; RASSF2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, HL-60, Mouse spleen, Mouse thymus, Rat thymus, U-937	Application	ELISA, WB

Cat.No

ADA-13387A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

RASSF2

Target Synonyms

CENP-34; RASFADIN; RASSF2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, HL-60, Mouse spleen, Mouse thymus, Rat thymus, U-937

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2 (P50749).	Target Species	Human
Immunogen Sequence	HTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEEIAETPATI	Uniprot ID	P50749

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2 (P50749).

Target Species

Human

Immunogen Sequence

HTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEEIAETPATI

Uniprot ID

P50749

Background Information

Uniprot Id

P50749
Target Species

Human
Target Name

RASSF2
Target Full Name

Ras association domain-containing protein 2
Target Function

Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Target Subcellular Location

Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
Target Tissue Specificity

Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Target Synonyms

CENP 34; Centromere protein 34; Ras association (RalGDS/AF 6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain containing protein 2; Ras association domain-containing protein 2; RASF2_HUMAN; RASFADIN; RASSF2; RP4-599I11.1
Target Background

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.

Rabbit anti-Human RASSF2 Monoclonal Antibody

Specifications

Immunogen Information

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