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| Cat.No | ACP01617 | Target Name | RNASE2 |
|---|---|---|---|
| Target Synonyms | (Eosinophil-derived neurotoxin)(RNase UpI-2)(Ribonuclease 2)(RNase 2)(Ribonuclease US) | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Expression Range | 28-161aa |
| Mol Weight | 44.4 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P10153 |
|---|
Uniprot Id
P10153
Target Species
Human
Target Name
RNASE2
Target Full Name
Non-secretory ribonuclease
Target Function
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Target Subcellular Location
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Target Protein Families
Pancreatic ribonuclease family
Target Tissue Specificity
Liver, lung, spleen, leukocytes and body fluids.
Target Research Area
Immunology
Target Synonyms
RNASE2; EDN; RNS2; Non-secretory ribonuclease; EC 4.6.1.18; Eosinophil-derived neurotoxin; RNase UpI-2; Ribonuclease 2; RNase 2; Ribonuclease US
Target Background
The protein encoded by this gene is a non-secretory ribonuclease that belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein antimicrobial activity against viruses.
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