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| Cat.No | ACP03422 | Target Name | AKR7A3 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-331aa | Mol Weight | 64.2kDa |
| Protein Length | Full Length of BC025709 | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95154 |
|---|
Uniprot Id
O95154
Target Species
Human
Target Name
AKR7A3
Target Full Name
Aflatoxin B1 aldehyde reductase member 3
Target Function
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Aldo/keto reductase family, Aldo/keto reductase 2 subfamily
Target Tissue Specificity
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Target Research Area
Signal Transduction
Target Synonyms
AFAR 2; AFAR2; AFB1 aldehyde reductase 2; AFB1 AR 2; AFB1-AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Akr7a3; Aldo keto reductase family 7 member A3; ARK73_HUMAN; OTTHUMP00000002623
Target Background
Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.
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