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Recombinant Human Lactoperoxidase (LPO)

ACP03647

Number
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Specifications


Cat.No ACP03647 Target NameLPO
Target SynonymsLPO; SAPX; Lactoperoxidase; LPO; EC 1.11.1.7; Salivary peroxidase; SPOFormLiquid or Lyophilized powder
Expression SystemMammalian cellExpression Range81-712aa
Mol Weight76.6 kDaProtein LengthFull Length of Mature Protein
PurityGreater than 85% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP22079
Background Information
  • Uniprot Id

    P22079

  • Target Species

    Human

  • Target Name

    LPO

  • Target Full Name

    Lactoperoxidase

  • Target Function

    Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peroxidase family, XPO subfamily

  • Target Tissue Specificity

    Mammary gland; milk and salivary gland. Found in bronchial submucosal glands.

  • Target Research Area

    Others

  • Target Synonyms

    LPO; SAPX; Lactoperoxidase; LPO; EC 1.11.1.7; Salivary peroxidase; SPO

  • Target Background

    This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

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