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Recombinant Human Probable cation-transporting ATPase 13A1 (ATP13A1), Truncated

ACP05770

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05770 Target NameATP13A1
Target SynonymsATP13A1; ATP13A; KIAA1825; CGI-152Manganese-transporting ATPase 13A1; EC 7.2.2.-FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9HD20
Background Information
  • Uniprot Id

    Q9HD20

  • Target Species

    Human

  • Target Name

    ATP13A1

  • Target Full Name

    Endoplasmic reticulum transmembrane helix translocase

  • Target Function

    Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    Cation transport ATPase (P-type) (TC 3.A.3) family, Type V subfamily

  • Target Synonyms

    ATP13A1; ATP13A; KIAA1825; CGI-152Manganese-transporting ATPase 13A1; EC 7.2.2.-

  • Target Background

    Enables transmembrane protein dislocase activity. Involved in extraction of mislocalized protein from ER membrane. Located in membrane.

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