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Recombinant Human Solute carrier family 22 member 9 (SLC22A9), Truncated

ACP05988

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05988 Target NameSLC22A9
Target SynonymsSLC22A9; hOAT4; OAT7; UST3; Solute carrier family 22 member 9; Organic anion transporter 7FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IVM8
Background Information
  • Uniprot Id

    Q8IVM8

  • Target Species

    Human

  • Target Name

    SLC22A9

  • Target Full Name

    Organic anion transporter 7

  • Target Function

    Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes.

  • Target Subcellular Location

    Basolateral cell membrane; Multi-pass membrane protein. Note=Enriched at the sinusoidal part of the plasma membrane.

  • Target Protein Families

    Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family

  • Target Tissue Specificity

    Specifically expressed in liver by hepatocytes (at protein level).

  • Target Synonyms

    SLC22A9; hOAT4; OAT7; UST3; Solute carrier family 22 member 9; Organic anion transporter 7

  • Target Background

    Enables anion:anion antiporter activity; short-chain fatty acid transmembrane transporter activity; and sodium-independent organic anion transmembrane transporter activity. Involved in hormone transport; short-chain fatty acid import; and sodium-independent organic anion transport. Located in basolateral plasma membrane.

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