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| Cat.No | ACP06156 | Target Name | RIC1 |
|---|---|---|---|
| Target Synonyms | Connexin-43-interacting protein of 150 kDa; Kiaa1432; Protein RIC1 homolog; RIC1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q4ADV7 |
|---|
Uniprot Id
Q4ADV7
Target Species
Human
Target Name
RIC1
Target Full Name
Guanine nucleotide exchange factor subunit RIC1
Target Function
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
Target Subcellular Location
Cytoplasm, cytosol. Membrane.
Target Protein Families
RIC1 family
Target Tissue Specificity
Present in kidney and various cell lines (at protein level). Widely expressed at low level.
Target Synonyms
Connexin-43-interacting protein of 150 kDa; Kiaa1432; Protein RIC1 homolog; RIC1_HUMAN
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