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| Cat.No | ACP06846 | Target Name | FAM168B |
|---|---|---|---|
| Target Synonyms | FAM168B; KIAA0280L; MANI; Myelin-associated neurite-outgrowth inhibitor; Mani; p20 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A1KXE4 |
|---|
Uniprot Id
A1KXE4
Target Species
Human
Target Name
FAM168B
Target Full Name
Myelin-associated neurite-outgrowth inhibitor
Target Function
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.
Target Subcellular Location
Cytoplasm, perinuclear region. Cell membrane; Multi-pass membrane protein. Cell projection, axon.
Target Protein Families
FAM168 family
Target Tissue Specificity
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level).
Target Synonyms
FAM168B; KIAA0280L; MANI; Myelin-associated neurite-outgrowth inhibitor; Mani; p20
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