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| Cat.No | ACP07013 | Target Name | GPR6 |
|---|---|---|---|
| Target Synonyms | GPR6; G-protein coupled receptor 6; Sphingosine 1-phosphate receptor GPR6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P46095 |
|---|
Uniprot Id
P46095
Target Species
Human
Target Name
GPR6
Target Full Name
G-protein coupled receptor 6
Target Function
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.
Target Protein Families
G-protein coupled receptor 1 family
Target Synonyms
GPR6; G-protein coupled receptor 6; Sphingosine 1-phosphate receptor GPR6
Target Background
Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane.
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