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| Cat.No | ACP07494 | Target Name | SCAMP5 |
|---|---|---|---|
| Target Synonyms | SCAMP5; Secretory carrier-associated membrane protein 5; Secretory carrier membrane protein 5; hSCAMP5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TAC9 |
|---|
Uniprot Id
Q8TAC9
Target Species
Human
Target Name
SCAMP5
Target Full Name
Secretory carrier-associated membrane protein 5
Target Function
Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Target Protein Families
SCAMP family, SCAMP5 subfamily
Target Tissue Specificity
Expressed both by neuronal and non-neuronal tissues. Expressed in brain, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is expressed by the follicular epithelial c
Target Synonyms
SCAMP5; Secretory carrier-associated membrane protein 5; Secretory carrier membrane protein 5; hSCAMP5
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