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| Cat.No | ACP11078 | Target Name | DOHH |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-302 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BU89 |
|---|
Uniprot Id
Q9BU89
Target Species
Human
Target Name
DOHH
Target Full Name
Deoxyhypusine hydroxylase
Target Function
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Target Protein Families
Deoxyhypusine hydroxylase family
Target Synonyms
Deoxyhypusine dioxygenase; Deoxyhypusine hydroxylase; Deoxyhypusine hydroxylase/monooxygenase ; Deoxyhypusine monooxygenase; Dohh; DOHH_HUMAN; hDOHH; HEAT like (PBS lyase) repeat containing 1; HEAT like PBS lyase repeat containing ; HEAT like repeat containing protein 1 ; HEAT-like repeat-containing protein 1; HLRC1; MGC4293
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