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Recombinant Human Homeobox expressed in ES cells 1 (HESX1)

ACP11660

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11660 Target NameHESX1
Target SynonymsHESX1; HANF; Homeobox expressed in ES cells 1; Homeobox protein ANF; hAnfFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-185
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UBX0
Background Information
  • Uniprot Id

    Q9UBX0

  • Target Species

    Human

  • Target Name

    HESX1

  • Target Full Name

    Homeobox expressed in ES cells 1

  • Target Function

    Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.

  • Target Involvement

    Septooptic dysplasia (SOD); Growth hormone deficiency with pituitary anomalies (GHDPA); Pituitary hormone deficiency, combined, 5 (CPHD5)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ANF homeobox family

  • Target Synonyms

    HESX1; HANF; Homeobox expressed in ES cells 1; Homeobox protein ANF; hAnf

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