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Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 2 (NUDT4)

ACP11975

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11975 Target NameNUDT4
Target Synonyms5''' P1, NUDT4; DIPP2; KIAA0487; HDCMB47P; Diphosphoinositol polyphosphate phosphohydrolase 2; DIPP-2; EC 3.6.1.52; Diadenosine 5', P6-hexaphosphate hydrolase 2; Nucleoside diphosphate-linked moiety X motif 4; Nudix motif 4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-180
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NZJ9
Background Information
  • Uniprot Id

    Q9NZJ9

  • Target Species

    Human

  • Target Name

    NUDT4

  • Target Full Name

    Diphosphoinositol polyphosphate phosphohydrolase 2

  • Target Function

    Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Can also catalyze the hydrolysis of diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) but not diadenosine 5',5'''-P1,P5-pentaphosphate (Ap5A) and the major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Nudix hydrolase family, DIPP subfamily

  • Target Tissue Specificity

    Expressed in heart and, at lower level in skeletal muscle, pancreas and kidney.

  • Target Synonyms

    NUDT4; DIPP2; KIAA0487; HDCMB47P; Diphosphoinositol polyphosphate phosphohydrolase 2; DIPP-2; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; Nucleoside diphosphate-linked moiety X motif 4; Nudix motif 4

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