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Recombinant Human Beta,beta-carotene 15,15′-monooxygenase (BCMO1)

ACP12072

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12072 Target NameBCO1
Target Synonyms15'-monooxygenase 1; Beta-carotene dioxygenase 1; FLJ10730, 15'-monooxygenase; beta-carotene 15, BCDO; BCDO1; BCDO1_HUMAN; BCMO; Bcmo1; BCO; BCO1; Beta, beta-carotene 15FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-547
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9HAY6
Background Information
  • Uniprot Id

    Q9HAY6

  • Target Species

    Human

  • Target Name

    BCO1

  • Target Full Name

    Beta,beta-carotene 15,15'-dioxygenase

  • Target Function

    Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.

  • Target Involvement

    Hypercarotenemia and vitamin A deficiency, autosomal dominant (ADHVAD)

  • Target Protein Families

    Carotenoid oxygenase family

  • Target Tissue Specificity

    Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.

  • Target Synonyms

    BCDO; BCDO1; BCDO1_HUMAN; BCMO; Bcmo1; BCO; BCO1; Beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1; Beta-carotene dioxygenase 1; FLJ10730

  • Target Background

    Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta, beta-carotene into two retinal molecules.

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