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| Cat.No | ACP12072 | Target Name | BCO1 |
|---|---|---|---|
| Target Synonyms | 15'-monooxygenase 1; Beta-carotene dioxygenase 1; FLJ10730, 15'-monooxygenase; beta-carotene 15, BCDO; BCDO1; BCDO1_HUMAN; BCMO; Bcmo1; BCO; BCO1; Beta, beta-carotene 15 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-547 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HAY6 |
|---|
Uniprot Id
Q9HAY6
Target Species
Human
Target Name
BCO1
Target Full Name
Beta,beta-carotene 15,15'-dioxygenase
Target Function
Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.
Target Involvement
Hypercarotenemia and vitamin A deficiency, autosomal dominant (ADHVAD)
Target Protein Families
Carotenoid oxygenase family
Target Tissue Specificity
Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.
Target Synonyms
BCDO; BCDO1; BCDO1_HUMAN; BCMO; Bcmo1; BCO; BCO1; Beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1; Beta-carotene dioxygenase 1; FLJ10730
Target Background
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta, beta-carotene into two retinal molecules.
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