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| Cat.No | ACP12074 | Target Name | SIAE |
|---|---|---|---|
| Target Synonyms | SIAE; YSG2; Sialate O-acetylesterase; EC 3.1.1.53; H-Lse; Sialic acid-specific 9-O-acetylesterase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 24-523 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HAT2 |
|---|
Uniprot Id
Q9HAT2
Target Species
Human
Target Name
SIAE
Target Full Name
Sialate O-acetylesterase
Target Function
Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.
Target Involvement
Autoimmune disease 6 (AIS6)
Target Subcellular Location
Lysosome. Secreted.
Target Tissue Specificity
Widely expressed with high expression in the testis, prostate, and colon.
Target Synonyms
SIAE; YSG2; Sialate O-acetylesterase; EC 3.1.1.53; H-Lse; Sialic acid-specific 9-O-acetylesterase
Target Background
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.
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