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Recombinant Human Transcription elongation factor A protein-like 7 (TCEAL7)

ACP12209

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12209 Target NameTCEAL7
Target SynonymsTCEAL7; Transcription elongation factor A protein-like 7; TCEA-like protein 7; Transcription elongation factor S-II protein-like 7FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-100
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BRU2
Background Information
  • Uniprot Id

    Q9BRU2

  • Target Species

    Human

  • Target Name

    TCEAL7

  • Target Full Name

    Transcription elongation factor A protein-like 7

  • Target Function

    Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    TFS-II family, TFA subfamily

  • Target Tissue Specificity

    Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors.

  • Target Synonyms

    TCEAL7; Transcription elongation factor A protein-like 7; TCEA-like protein 7; Transcription elongation factor S-II protein-like 7

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