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Recombinant Human Telomerase protein component 1 (TEP1), Truncated

ACP12466

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12466 Target NameTEP1
Target SynonymsTEP1; TLP1; TP1; Telomerase protein component 1; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homologFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ99973
Background Information
  • Uniprot Id

    Q99973

  • Target Species

    Human

  • Target Name

    TEP1

  • Target Full Name

    Telomerase protein component 1

  • Target Function

    Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.

  • Target Subcellular Location

    Nucleus. Chromosome, telomere.

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    TEP1; TLP1; TP1; Telomerase protein component 1; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog

  • Target Background

    This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants.

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