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Recombinant Human Protein maelstrom homolog (MAEL)

ACP13780

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Specifications

Cat.No	ACP13780	Target Name	MAEL
Target Synonyms	cancer/testis antigen 128; CT128; FLJ14904; mael; MAEL_HUMAN; maelstrom homolog (Drosophila); Maelstrom homolog; OTTHUMP00000032344; Protein maelstrom homolog; RP11-102C16.1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-434
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96JY0

Background Information

Uniprot Id

Q96JY0
Target Species

Human
Target Name

MAEL
Target Full Name

Protein maelstrom homolog
Target Function

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.
Target Subcellular Location

Cytoplasm. Nucleus.
Target Protein Families

Maelstrom family
Target Tissue Specificity

Testis-specific. Expressed in various cancer cell lines, probably due to demethylation of its promoter.
Target Synonyms

cancer/testis antigen 128; CT128; FLJ14904; mael; MAEL_HUMAN; maelstrom homolog (Drosophila); Maelstrom homolog; OTTHUMP00000032344; Protein maelstrom homolog; RP11-102C16.1

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Recombinant Human Protein maelstrom homolog (MAEL)

Specifications

Immunogen Information

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