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| Cat.No | ACP14547 | Target Name | AGBL3 |
|---|---|---|---|
| Target Synonyms | CCP3; Agbl3; ATP/GTP-binding protein-like 3; CBPC3_HUMAN; Cytosolic carboxypeptidase 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NEM8 |
|---|
Uniprot Id
Q8NEM8
Target Species
Human
Target Name
AGBL3
Target Full Name
Cytosolic carboxypeptidase 3
Target Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins.; Metallocarboxypeptidase that mediates tubulin deglutamylation.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
Peptidase M14 family
Target Synonyms
CCP3; Agbl3; ATP/GTP-binding protein-like 3; CBPC3_HUMAN; Cytosolic carboxypeptidase 3
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