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| Cat.No | ACP15809 | Target Name | TTI2 |
|---|---|---|---|
| Target Synonyms | C8orf41; CH041_HUMAN; TELO2 interacting protein 2provided; TTI2; Uncharacterized protein C8orf41 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-508 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6NXR4 |
|---|
Uniprot Id
Q6NXR4
Target Species
Human
Target Name
TTI2
Target Full Name
TELO2-interacting protein 2
Target Function
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Target Involvement
Mental retardation, autosomal recessive 39 (MRT39)
Target Protein Families
TTI2 family
Target Synonyms
C8orf41; CH041_HUMAN; TELO2 interacting protein 2provided; TTI2; Uncharacterized protein C8orf41
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