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| Cat.No | ACP15992 | Target Name | TSSK4 |
|---|---|---|---|
| Target Synonyms | C14orf20; Serine/threonine-protein kinase 22E; STK22E; Testis-specific kinase 4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Tssk4; TSSK4_HUMAN; TSSK5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-328 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6SA08 |
|---|
Uniprot Id
Q6SA08
Target Species
Human
Target Name
TSSK4
Target Full Name
Testis-specific serine/threonine-protein kinase 4
Target Function
Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
Target Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Tissue Specificity
Expressed only in the testis.
Target Synonyms
C14orf20; Serine/threonine-protein kinase 22E; STK22E; Testis-specific kinase 4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Tssk4; TSSK4_HUMAN; TSSK5
Target Background
This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.
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