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| Cat.No | ACP16058 | Target Name | NUDT18 |
|---|---|---|---|
| Target Synonyms | 2-hydroxy-dADP phosphatase; 7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-323 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZVK8 |
|---|
Uniprot Id
Q6ZVK8
Target Species
Human
Target Name
NUDT18
Target Full Name
8-oxo-dGDP phosphatase NUDT18
Target Function
Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools.
Target Protein Families
Nudix hydrolase family
Target Synonyms
2-hydroxy-dADP phosphatase; 7,8-dihydro-8-oxoguanine phosphatase; 8-oxo-dGDP phosphatase NUDT18; BC036718; FLJ22494; MGC38179; MTH3; mutT homolog 3; mutT human homolog 3; Nucleoside diphosphate linked moiety X motif 18; Nucleoside diphosphate-linked moiety X motif 18; NUD18_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 18; Nudix motif 18; NUDT 18; Nudt18; RGD1311802
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