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| Cat.No | ACP17683 | Target Name | CSPP1 |
|---|---|---|---|
| Target Synonyms | CSPP1; CSPPCentrosome and spindle pole-associated protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q1MSJ5 |
|---|
Uniprot Id
Q1MSJ5
Target Species
Human
Target Name
CSPP1
Target Full Name
Centrosome and spindle pole-associated protein 1
Target Function
May play a role in cell-cycle-dependent microtubule organization.
Target Involvement
Joubert syndrome 21 (JBTS21)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with mitotic spindles.
Target Tissue Specificity
Expressed in adult and fetal brain with enrichment in the cerebellum. Detected in testis.
Target Synonyms
CSPP1; CSPPCentrosome and spindle pole-associated protein 1
Target Background
This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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