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| Cat.No | ACP18356 | Target Name | HLX |
|---|---|---|---|
| Target Synonyms | H2.0 like homeo box 1; H2.0 like homeobox 1; H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HB24; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-488 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14774 |
|---|
Uniprot Id
Q14774
Target Species
Human
Target Name
HLX
Target Full Name
H2.0-like homeobox protein
Target Function
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.
Target Subcellular Location
Nucleus.
Target Protein Families
H2.0 homeobox family
Target Tissue Specificity
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Target Synonyms
H2.0 like homeo box 1; H2.0 like homeobox 1; H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HB24; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1
Target Background
Enables sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including animal organ development; enteric nervous system development; and regulation of T-helper cell differentiation. Predicted to be located in nucleus. Predicted to be part of chromatin.
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